A Reservoir ofMoraxella catarrhalisin Human Pharyngeal Lymphoid Tissue

A reservoir of Moraxella catarrhalis in human pharyngeal lymphoid tissue.

BACKGROUND Early exposure of infants and long-term immunity suggest that colonization with Moraxella catarrhalis is more frequent than is determined by routine culture. We characterized a reservoir of M. catarrhalis in pharyngeal lymphoid tissue. METHODS Tissue from 40 patients (median age, 7.1 years) undergoing elective tonsillectomy and/or adenoidectomy was analyzed for the presence of M. c...

Pharyngeal gonorrhoea: the forgotten reservoir.

Prevalence and cellular reservoir of latent human herpesvirus 6 in tonsillar lymphoid tissue.

There are few studies that examine prevalence, quantity, and cellular proclivity of latent human herpesvirus 6 (HHV-6) in healthy populations. We examined 69 tonsils with paired blood specimens from children without evidence of acute infection. By polymerase chain reaction (PCR), HHV-6 was detected at low levels in 100% of tonsils and 39% of blood samples (n = 27), suggesting that prevalence of...

Pharyngeal gonorrhea: an important reservoir of infection?

In 2008, 1330,000 cases of gonorrhea were reported to the Centers for Disease Control and Prevention (CDC). The actual number of infections per year is thought to be much higher because of underdetection and underreporting [1]. Neisseria gonorrhoeae can cause cervicitis, urethritis, proctitis, pelvic inflammatory disease with long-term sequelae (eg, infertility, ectopic pregnancy, and chronic p...

Cell Differentiation in Human Lymphoid Tissue

In the last two decades, anatomic compartmentalization of T and B cells within lymphoid tissues has been demonstrated in a wide variety of species, including man (1-5). T cells are located in the paracortical or interfollicular regions of lymph nodes and in the lymphoid tissues of the intestine and tonsil, whereas in the spleen, T cells are found primarily in the periarteriolar region of the Ma...